Understand how you can increase your immune system with natural mushrooms!
Here is the research discussed in this episode:
1. The Herb-Drug Interaction Systematic Review (Turkey Tail, neuropathy, and chemotherapy combinations)
Lam CS, Cheng LP, Zhou LM, Cheung YT, Zuo Z. Herb-drug interactions between the medicinal mushrooms Lingzhi and Yunzhi and cytotoxic anticancer drugs: a systematic review. Chinese Medicine. 2020;15:75. doi:10.1186/s13020-020-00356-4. PMC7382813.
2. Dose-Dependent Turkey Tail Trial (3, 6, 9 gram mycelium extract, NK cell recovery, breast cancer post-radiation)
Torkelson CJ, Sweet E, Martzen MR, Sasagawa M, Wenner CA, Gay J, Putiri A, Standish LJ. Phase 1 clinical trial of Trametes versicolor in women with breast cancer. ISRN Oncology. 2012;2012:251632. doi:10.5402/2012/251632. PMID:22701186. PMC3369477.
3. Hallmarks of Cancer and Medicinal Mushrooms Review
Frontiers in Cancer Control and Society. Medicinal mushrooms and the hallmarks of cancer: mechanistic insights for complementary chemotherapy. Published March 30, 2026. doi:10.3389/fcacs.2026.1774081.
4. Antioxidants Do Not Interfere With Chemotherapy (systematic review)
Block KI, Koch AC, Mead MN, Tothy PK, Newman RA, Gyllenhaal C. Impact of antioxidant supplementation on chemotherapeutic efficacy: a systematic review of the evidence from randomized controlled trials. Cancer Treatment Reviews. 2007;33(5):407-418. doi:10.1016/j.ctrv.2007.01.005. PMID:17367938.
5. Turkey Tail and Reishi Clearing HPV 16/18 (88% clearance, preliminary clinical trial)
Donatini B. Control of oral human papillomavirus (HPV) by medicinal mushrooms, Trametes versicolor and Ganoderma lucidum: a preliminary clinical trial. International Journal of Medicinal Mushrooms. 2014;16(5):497-498. doi:10.1615/IntJMedMushrooms.v16.i5.80. PMID:25271984.
6. Beta-Glucan Combined With Checkpoint Inhibitors (PD-1/PD-L1, advanced cancer, reversed resistance)
Wang M, Bai Y, Pei J, et al. Beta-glucan combined with PD-1/PD-L1 checkpoint blockade for immunotherapy in patients with advanced cancer. Frontiers in Pharmacology. 2022;13:887457. doi:10.3389/fphar.2022.887457. PMC9084312.
7. Turkey Tail Breast Cancer Immune Therapy Paper
Standish LJ, Wenner CA, Sweet ES, Bridge C, Nelson A, Martzen M, Novack J, Torkelson C. Trametes versicolor mushroom immune therapy in breast cancer. Journal of the Society for Integrative Oncology. 2008;6(3):122-128. PMID:19087769. PMC2845472.
8. Fungal Beta-Glucans as Adjuvants in Cancer Patients: Systematic Review of Clinical Trials
Steimbach L, Borgmann AV, Gomar GG, et al. Fungal beta-glucans as adjuvants for treating cancer patients: a systematic review of clinical trials. Clinical Nutrition. 2021;40(5):3104-3113. doi:10.1016/j.clnu.2020.11.035. PMID:33341310.